Advertise Your Data Via Cafe Variome "Central"

Cafe Variome "Central" (available at was originally designed to function as a clearinghouse and exchange portal for gene variant (mutation) data produced by diagnostics laboratories and all available variants from public repositories, offering users a portal through which to announce, discover and acquire a comprehensive listing of observed neutral and disease-causing gene variants in patients and unaffected individuals.

Cafe Variome can help you publish your data and share with others in a number of different ways:

A. Diagnostic Software

Cafe Variome has worked closely with the providers of mutation interpretation software used in diagnostic laboratories to produce versions of these tools that will allow you to submit sequence variants directly to a Cafe Variome installation.

The following software now offers this functionality:

- Gensearch (PhenoSystems). See the following page for details of how to submit.

- Alamut (Interactive Biosoftware). See the following page for details of how to submit.

Providers of other diagnostic software are encouraged to contact us to discuss enabling similar functionality in their own tools.

B. Upload to Cafe Variome "Central"

If you do not use software that is currently supported by Cafe Variome or you wish to upload variants in bulk you may use the built in data import facility to import variants.

Variants can be added through the curators interface of Cafe Variome, contact us in order to have your account set as a curator.

C. Hosted and "in-a-box" versions

We recognise that some users may not wish to use the central version of Cafe Variome and instead create their own private installations. In order to facilitate this we offer both a fully hosted version (on University of Leicester servers) and an in-a-box version to interested collaborators.

Contact us to discuss either of these options.